The image depicts a person wearing a plaid shirt who is throwing their head and hands up dramatically in front of a colorful sunset sky. The setting sun is visible in the lower right corner of the image, casting the bottom of the frame in a hazy orange glow. A thin sliver of crescent moon is visible in the upper left corner of the image, surrounded by a navy blue night sky. In between the two, in the middle of the poster, is a line of clouds. At the bottom of the poster, behind the person who is throwing their hands up, are several more hands, which are slightly transparent and grasping up at the sky. Just below the moon is the film's title, "Two Spirits," with the word "Two" in orange and the word "Spirits" in light blue. Beneath the title is the following text introducing the topic of the film: "Fred Martinez was a Navajo boy who was also a girl. In an earlier era, he would have been revered. Instead, he was murdered."